ArticleWellens HJ.
Circulation. 1978 May;57(5):845-53.
A review is given on the use of programmed electrical stimulation of the heart in patients suffering from tachycardia. The application of this technique makes it possible to evaluate mechanisms of tachycardia directly in the human heart. By repeating the same stimulation program following drug administration the effect of drugs on arrhythmia mechanisms can be studied. There are several factors, however, that influence the amount of information on mechanism and pathway of tachycardia and selection of appropriate therapy that can be obtained during the study. These factors as well as how information obtained programmed electrical stimulation of the heart has resulted in a better use of the 12-lead electrocardiogram as a diagnostic tool are discussed.